This has been happening since I got a new computer (Vista, GeForce 8600 GTS, 24" widescreen, etc), and i can't figure out what hte deal is. I have it running at its max resolution (1920x1200), and the colors are at "highest" (32 bit) I'll copy an image straight from the card and either open it up in the Windows Picture Viewer or even Photoshop CS3 ... doesn't matter what the program is ... and it looks like the image on the left. All blotchy, the colors are all screwed up, etc. Then I can upload that same exact image to my Flickr account, go to the flickr site, and the image looks just fine. This is the best way I can show what the deal is. Am I missing some sort of color manager or something? I don't get it. Image on the left was opened in CS3 from an image file on my desktop. Image on the right is that exact same image uploaded to Flickr, and then opened in IE.