Thoughts on Leucine?

Discussion in 'Fitness & Nutrition' started by Ribbie, Oct 7, 2008.

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  1. Ribbie

    Ribbie OT Supporter

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    I'm contemplating picking some up but I was curious if anyone had any experience with the product that they'd like to share with me.

    Thoughts/comments/ brand suggestions?

    http://en.wikipedia.org/wiki/Leucine
     
  2. Damnation

    Damnation OT Supporter

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    read that it's good to take..cheaper than xtend
     
  3. Marix

    Marix OT Supporter

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    New T-nation supplement is leucine but they're pimping it as some sort of food aditive

    I don't know a huge amount but I'm going to say you're not going to see any profound difference if you're bulking. Maybe it would help preserve muscle on a cut... I dunno
     
  4. Spidey

    Spidey Member

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  5. Damnation

    Damnation OT Supporter

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  6. vudoodoodoo

    vudoodoodoo New Member

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    scoop some in your post work out shake. done.
     
  7. Ribbie

    Ribbie OT Supporter

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    Yeah that's actually what sparked the thread. I have heard about it before but the tnation article this morning reminded me about it.


    Currently taking whey and glutamine pre-post workout. Just wondered if anyone had any experience with it and what their thoughts on it were.

    Basically, is it just a useless supplement or will I see a benefit from it?
     
  8. Spur

    Spur Boomer

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    truth
     
  9. deznutz

    deznutz New Member

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  10. Damnation

    Damnation OT Supporter

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    hell ya, its the best
     
  11. Drewski

    Drewski New Member

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  12. Ceaze

    Ceaze https://hearthis.at/DoYouEvenUplift Moderator

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    the theory in taking it in free form is that you get a big spike at once in the bloodstream, whole protein still has to be digested
     
  13. timberwolf

    timberwolf New Member

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    Aren't di and tri-peptides absorbed even faster than free form?
     
  14. Ceaze

    Ceaze https://hearthis.at/DoYouEvenUplift Moderator

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    A recent study found that whey isolate resulted in faster absorption of aminos than hydrolyzed whey.
     
  15. timberwolf

    timberwolf New Member

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    I thought it was whey hydrolysates> free form > whey isolate> whey concentrate.
     
  16. Ceaze

    Ceaze https://hearthis.at/DoYouEvenUplift Moderator

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    Int J Food Sci Nutr. 2008 May 8:1-11.

    Plasma amino acid response after ingestion of different whey protein fractions.

    Farnfield MM, Trenerry C, Carey KA, Cameron-Smith D.

    School of Exercise and Nutrition Sciences, Deakin University, Burwood, Victoria, Australia.

    Background and objectives The digestion rate of proteins and subsequent absorption of amino acids can independently modulate protein metabolism. The objective of the present study was to examine the blood amino acid response to whey protein isolate (WPI), beta-lactoglobulin-enriched WPI, hydrolysed WPI and a flavour-identical control. Methods Eight healthy adults (four female, four male) were recruited (mean+/-standard error of the mean: age, 27.0+/-0.76 years; body mass index, 23.2+/-0.8 kg/cm(2)) and after an overnight fast consumed 500 ml of each drink, each containing 25g protein, in a cross-over design. Blood was taken at rest and then every 15 min for 2 h post ingestion. Results Ingesting the beta-lactoglobulin-enriched WPI drink resulted in significantly greater plasma leucine concentrations at 45-120 min and significantly greater branched-chain amino acid concentrations at 60-105 min post ingestion compared with hydrolysed WPI. No differences were observed between WPI and beta-lactoglobulin-enriched WPI, and all protein drinks resulted in elevated blood amino acids compared with flavour-identical control. Conclusions In conclusion, whole proteins resulted in a more rapid absorption of leucine and branched-chain amino acid into the blood compared with the hydrolysed molecular form of whey protein.

    PMID: 18608553
     
  17. Ceaze

    Ceaze https://hearthis.at/DoYouEvenUplift Moderator

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    wish they compared free-form
     
  18. {hydro}

    {hydro} OT Supporter

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    I like drinking xtend during my workout because I think my body starts eating itself when I do cardio after sum maximum iron pumpage.
     
  19. Ribbie

    Ribbie OT Supporter

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    Here's the article from t-nation that I was referring to.

    http://www.t-nation.com/free_online...t_unleash_the_full_anabolic_potential_of_food
     
  20. Ceaze

    Ceaze https://hearthis.at/DoYouEvenUplift Moderator

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    taking t-nation's word on something they sell :ugh:
     
  21. Ribbie

    Ribbie OT Supporter

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    :rofl: that's why I'm asking about personal experience you meatheads
     
  22. JeremyD

    JeremyD New Member

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    I use it during intense cardio sessions, especially when I do fasted cardio. It's cheaper than BCAA's, and it's been shown that most of the benefits of BCAA's are derived from the luecine anyway.
     
  23. Marix

    Marix OT Supporter

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    Kinda.

    Leucine is what you could call the rate limiting factor. If there is tons of other amino acids, but no leucine, you won't build muscle. Some people call it the anabolic switch and if there is lots of leucine available, there may be more protein synthesis.

    But like I said earlier, I will remain sceptical. I would still just use fast carb + protein after a workout. And just eat slow digesting protein sources (powdered blends, dairy, meat etc) for the rest of the day.

    IMO, T-nation is just pushing things too far in terms of their advertising. They talk about integrity but it seems to me that the authors and trainers will say just about anything to try and sell their stuff.
    They always talk about the quality of their procucts but to be honest, their products are good but they're not great... plus they're horribly overpriced. Surge is basically just dextrose, maltodextrin + whey.. why the FUCK does it cost £30 for 800g of the stuff?! And even though they claim to be different, their protein bars are filled with just as much crap as any other.
     
  24. Ceaze

    Ceaze https://hearthis.at/DoYouEvenUplift Moderator

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    You know that leucine will only stimulate protein synthesis in the presence of other available EAA's?
     
  25. JeremyD

    JeremyD New Member

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    I've seen studies comparing ingestion of leucine to ingestion of a BCAA mix w/regards to protein synthesis and their was minimal difference. :dunno:
     
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