Ceaze, Pur etc. How big of a problem are corticosteroids in terms of muscle building

Discussion in 'Fitness & Nutrition' started by therealdeal, Aug 1, 2006.

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  1. therealdeal

    therealdeal New Member

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    say about 0.07mg/kg/day?
     
  2. Hpower

    Hpower GO GATORS

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    are you on them chronically or for a short period of time?
     
  3. therealdeal

    therealdeal New Member

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    good question

    chronically
     
  4. black jesus

    black jesus OT Supporter

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    get ready for weird growth shit on your back and face according to my pharmacist neighbor.
     
  5. slikna

    slikna Grenade

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    Im about to be on prednisone for a few weeks due to a full body case of poison oak thats gotten out of hand. How will this effect lifting / muscle mass? Anything to worry about since its just a short term time?
     
  6. therealdeal

    therealdeal New Member

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    Well I've been on it for like 15 years and I havent noticed anythign too extreme. Its hard to know what you mean by 'wierd growth shit' though :rofl:
     
  7. kronik85

    kronik85 New Member

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    i was put on a steroid for poison ivy, i can only assume it was prednisone. i didn't notice anything adverse, though i wasn't lifting all the time. i didn't notice myself losing weight or anything.
     
  8. Chris3G

    Chris3G Bullshark Testosterone

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    In conclusion, we observed different effects of prednisolone and triamcinolone in an equipotent dose and similar treatment, on muscle wasting, function and metabolism. Both corticosteroids were found to be associated with increased muscle glycogen concentrations and an increased recovery of the peripheral skeletal muscle in between two stimulation sessions. In addition, we observed no muscle wasting and alterations in peripheral skeletal muscle performance and metabolism after prednisolone treatment. Triamcinolone treatment however, was accompanied by muscle wasting of both the diaphragm and peripheral skeletal muscles, associated with type IIx/b atrophy of the diaphragm and a decreased fatigability of the diaphragm and peripheral skeletal muscles. In addition an increased glycolytic and oxidative capacity was found. Furthermore, decreased ATP, PCr and total adenine nucleotides and creatine pools were observed, suggesting metabolic impairment. Muscle protein metabolism was also disturbed, as indicated by an increased glutamine efflux from the muscle and an increased glutamine de novo production and membrane transport rates.

    should mention though that this study was done on rats.
     
  9. PurEvl

    PurEvl going out gassed and not half assed...

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    what kind? Like chris3g posted, they are not all created equal
     
  10. therealdeal

    therealdeal New Member

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    prednisone
     
  11. PurEvl

    PurEvl going out gassed and not half assed...

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    well chris's post reflects that...although some things i notice from people on it is they complain about severe bloat, aggression, headaches. I dont think you'er going to lose your muscle though.
     
  12. Hpower

    Hpower GO GATORS

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    well coriticosteriods are similar to cortisol, I would just expect weight gain, bloated look, you can get more fat deposited. I would imagine if you are on them for along time that it has definatly affected your ability to gain muscle. This could be dose dependent tho. I don't know at what dose the adverse effects get worse or are not really an issue.

    If you don't mind my asking what are you taking it for?
     
  13. therealdeal

    therealdeal New Member

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    Well thats prednisolone, which is moderately different, but I see your point. I mainly wondered if anyone had seen/read specific studies related to chronic corticosteroid use and its effect mainly on muscle building rather than maintaining. Thats cool though, thanks for the input.
     
  14. therealdeal

    therealdeal New Member

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    lupus, arthritis, kidney transplant
     
  15. 007

    007 Riden, sliden, whipin and dippin, my chrome strips

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    you thought of radiation to lower your immune system, and then lower doses?
     
  16. Peyomp

    Peyomp New Member

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    On a long enough time-line you might have slightly fewer gains in terms of muscle mass. But it won't be anything you will notice short-term. Or even long term. You might also tend to retain a little bit more bodyfat round the middle. I'd watch this, and adjust diet/cardio accordingly.
     
  17. GilgaMesH

    GilgaMesH Active Member

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    Having been on prednisone for a 6 month period (high dose), I can say that it made me lose a significant amount of muscle. A ridiculous amount actually and I have pics for proof. Pretty terrible compound to be on if you're loooking for muscle gain.
     
  18. edd91

    edd91 rebmeM weN

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    As i'm sure youre aware corticosteroids are associated with de-mineralisation of the bone, that would be my biggest concern, a safety one
     
  19. therealdeal

    therealdeal New Member

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    Luckily part of the reason I lift weights is to increase bone density. Probably kept me off extra meds for 3-4 years now.
     
  20. therealdeal

    therealdeal New Member

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    Like I say, I'm on it for like 3 reasons, that would treat only one. I did do chemo for a while though.
     
  21. PurEvl

    PurEvl going out gassed and not half assed...

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    here somethings i found googling as well

    Corticosteroids are powerful drugs which can quickly reduce swelling and inflammation, greatly improve symptoms and provoke incredible results. However, there are potential consequences and side effects. The power of corticosteroids should not be feared, but must be respected. To maximize benefits, but minimize potential side effects, steroids are usually prescribed in low doses or for short durations. The potent effect of corticosteroids can result in serious side effects which mimic Cushing's disease, a malfunction of the adrenal glands resulting in an overproduction of cortisol. The list of potential side effects is long and can include:

    increased appetite and weight gain
    deposits of fat in chest, face, upper back, and stomach
    water and salt retention leading to swelling and edema
    high blood pressure
    diabetes
    osteoporosis
    cataracts
    acne
    muscle weakness
    thinning of the skin
    increased susceptibility to infection
    stomach ulcers
    psychological problems such as depression
    adrenal suppression and crisis

    Side effects are minimized by taking the lowest doses possible (that still yields positive results) and following doctor's orders. It is important to avoid self regulation of the dosage, either by adding more or stopping the drug without a schedule. Steroids must be gradually reduced to permit the adrenal glands to resume natural cortisol production. Eliminating doses too quickly can result in adrenal crisis (a life-threatening state caused by insufficient levels of cortisol). Another possible complication to coming off steroids is withdrawal syndrome, or rebound effect, which is the body's exaggerated response to removal of the drug.
     
  22. Peyomp

    Peyomp New Member

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    Prednisone is not as bad as cortisone. I can't find my goodman and gillman's, but if I do I'll type up the summary on it.
     
  23. PurEvl

    PurEvl going out gassed and not half assed...

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    thanks
     
  24. Peyomp

    Peyomp New Member

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    Found it under my bed. Lemme see...
     
  25. PurEvl

    PurEvl going out gassed and not half assed...

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    type it up, its good info
     
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