I have a Glock 22 that has raised some concerns with me regarding the correct ammo to run. I have put approximately 1000 American Eagle 165 grain .40 S&W through it without issue. However, I have heard several surprising comments -- that this was a ticking time-bomb. One person recommended Winchester as a much safer choice. My question is what do I need to look for in ammo? I have Federal Personal Defense loaded in the mag for zombies -- but when at the range, I switch out to something much cheaper. The complaints I heard against the Federal was that the primer was too sensitive, and that was a problem with Glock's ability to fire out-of-battery. The winchester primer is claimed to be better. Comments? My concern is simply that Federal is over $6.00 cheaper per box of 50. For $100 I can basically get 10 boxes of Federal or only 6 boxes of Winchester. But at the same time, I don't want to kB my glock, or even worse -- lose a finger. Also, the Federal Premiums that I have are 135 grain, and were purchased at the recommendation of the clerk for home defense. Is that a good choice? The same clerk recommended the 165 grain for range use, as it was the cheapest and lightest round. The 180 grain is the same price as the 165. I understand the difference between 165 and 180 grain is the bullet weight, but how does this translate into balistics in terms of accuracy, kick, and the potential for a kB? Thank you for any input you may have.